Examining the utility of lower dose radiotherapy for localised primary ocular adnexal MALT lymphoma
نویسندگان
چکیده
منابع مشابه
A20 inactivation in ocular adnexal MALT lymphoma.
Recent studies showed A20 inactivation by deletion, mutation and promoter methylation in ocular adnexal mucosa-associated lymphoid tissue lymphoma. However, the incidences of A20 abnormalities and their clinical impact remain for the most part unknown. It is also unknown whether ABIN-1 and ABIN-2, the components of the A20 NF-κB inhibitor complex, are inactivated by genetic changes in ocular ad...
متن کاملUltra-low-dose radiotherapy for definitive management of ocular adnexal B-cell lymphoma.
BACKGROUND The purpose of this study was to report the response to and toxicity of ultra-low-dose radiotherapy (RT) for B-cell ocular adnexal lymphoma (OAL). METHODS We conducted a retrospective review of patients with indolent B-cell and mantle cell OAL treated with 4 Gy to the orbit(s) in two 2-Gy fractions. Disease response was assessed clinically and/or radiographically at 2 to 4-month in...
متن کاملTreatment outcome and risk analysis for cataract after radiotherapy of localized ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma
PURPOSE We retrospectively reviewed the results of radiotherapy for localized ocular adnexal MALT lymphoma (OAML) to investigate the risk factors of cataract. METHODS Sixty-seven patients with stage IE OAML treated with radiotherapy at Seoul St. Mary's Hospital from 2001 to 2016 were included. Median treatment dose was 30 Gy. Lens protection was done in 52 (76%) patients. Radiation therapy (R...
متن کاملRadiotherapy for early-stage primary ocular adnexal mucosa-associated lymphoid tissue lymphoma.
BACKGROUND Primary ocular adnexal mucosa-associated lymphoid tissue lymphoma (POAML) is a rare disease. The purpose of this study was to evaluate the treatment outcome and patterns of failure of patients with early-stage POAML treated with radiotherapy. PATIENTS AND METHODS From 1995 to 2008, 53 patients with early-stage POAML were reviewed. Tumors were categorized as either superficial or ma...
متن کاملRisk Potentiality of Frontline Radiotherapy Associated Cataract in Primary Ocular Adnexal Mucosa-associated Lymphoid Tissue Lymphoma
PURPOSE To elucidate risk potentiality of frontline radiotherapy associated cataracts in primary ocular adnexal mucosa-associated lymphoid tissue lymphoma (OAML). METHODS Data from eight consecutive patients of 41 total OAML patients who had undergone cataract surgery after frontline radiotherapy were analyzed. RESULTS The median patient age was 46 years (range, 36 to 69 years). The median ...
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ژورنال
عنوان ژورنال: Journal of Medical Radiation Sciences
سال: 2021
ISSN: 2051-3895,2051-3909
DOI: 10.1002/jmrs.464